Chest congestion occurs when mucus builds up in the airways, making breathing difficult and often causing discomfort. The best medicines for chest congestion include expectorants like guaifenesin, which help thin and loosen mucus, making it easier to expel. Decongestants such as pseudoephedrine reduce swelling in the nasal passages, easing airflow. Cough suppressants like dextromethorphan can be beneficial if a persistent cough is causing discomfort. For those with underlying conditions like asthma, bronchodilators may be necessary to open the airways. Combining these medications with steam inhalation and hydration can provide effective relief from chest congestion symptoms.